Saint Pope Eugene I (†657) was the bishop of Rome from 10 August 654 to his death. He was chosen to become Pope after the deposition and banishment of Martin I by Emperor Constans II over the dispute about Monothelitism. He is commemorated as the patron and namesake of the Cathedral of Saint Eugene in the Diocese of Santa Rosa in California.
Saint Pope Vitalian (†672) was the bishop of Rome from 30 July 657 to his death. His pontificate was marked by the dispute between the papacy and the imperial government in Constantinople over Monothelitism, which Rome condemned. Vitalian tried to resolve the dispute and had a conciliatory relationship with Emperor Constans II, who visited him in Rome and gave him gifts. Vitalian's pontificate also saw the secession of the Archbishopric of Ravenna from the papal authority.