Saint Peter († between AD 64 and 68), was one of the Twelve Apostles of Jesus Christ, leaders of the early Christian Church. He is also venerated as the "Apostle of the Apostles" and the first pope of the Roman Catholic Church, ordained by Jesus in the "Rock of My Church" dialogue in Matthew 16:18. The Christian churches all venerate Peter as a major saint and associate him with founding the Church of Antioch and later the Church in Rome. The Roman Martyrology assigns 29 June as the feast day of both Apostles Peter and Paul.

Saint Paul († AD 67), was an Apostle who taught the gospel of Christ to the first-century world and is generally considered one of the most important figures of the Apostolic Age founding several churches in Asia Minor and Europe.

Saint Anthony the Great (†356), was a Christian monk from Egypt, revered since his death as a saint. He is distinguished from other saints named Anthony such as Anthony of Padua, by various epithets: Saint Anthony, Anthony of Egypt, Anthony the Abbot, Anthony of the Desert, Anthony the Anchorite, Anthony the Hermit, and Anthony of Thebes. For his importance among the Desert Fathers and to all later Christian monasticism, he is also known as the Father of All Monks. The biography of Anthony's life by Athanasius of Alexandria helped to spread the concept of Christian monasticism, particularly in Western Europe via its Latin translations. Anthony was among the first known to go into the wilderness (about AD 270), which contributed to his renown. Accounts of Anthony enduring supernatural temptation during his sojourn in the Eastern Desert of Egypt inspired the depiction of his temptations in visual art and literature. Anthony is appealed to against infectious diseases, particularly skin diseases. In the past, many such afflictions, including ergotism, erysipelas, and shingles, were referred to as Saint Anthony's fire. His feast day is celebrated on 17 January among the Orthodox and Catholic churches and on Tobi 22 in the Coptic calendar.

Saint Thomas Aquinas, OP (†1274) is a Catholic saint and Doctor of the Church who was an Italian Dominican friar and Roman Catholic priest, and an immensely influential philosopher, theologian and jurist in the tradition of scholasticism, within which he is also known as the "Doctor Angelicus" and "Doctor Communis". He is a patron of Academics; against storms; against lightning; apologists; Aquino, Italy; Belcastro, Italy; book sellers; Catholic academies, schools, and universities; chastity; Falena, Italy; learning; pencil makers; philosophers; publishers; scholars; students; University of Sto. Tomas; Sto. Tomas, Batangas; and theologians.

Saint Aloysius Gonzaga, S.J. (Italian: Luigi Gonzaga; † 1591) was an Italian aristocrat who became a member of the Society of Jesus. While still a student at the Roman College, he died as a result of caring for the victims of an epidemic. He was beatified in 1605, and canonized in 1726. He is a patron of students, Christian youth, Jesuit scholastics, the blind, AIDS patients, AIDS caregivers.

Saint Mary Magdalene was a woman who, according to the texts included in the New Testament, traveled with Jesus as one of his followers and witnessed Jesus' crucifixion and resurrection. Within the four Gospels she is named at least 12 times, more than most of the apostles and she has been merited the title "Apostle to the apostles" by the Roman Catholic Church. Mary Magdalene is considered to be a saint by the Catholic, Eastern Orthodox, Anglican, and Lutheran churches—with a feast day of July 22. The Eastern Orthodox churches also commemorate her on the Sunday of the Myrrhbearers, the Orthodox equivalent of one of the Western Three Marys traditions. During the Middle Ages, Mary Magdalene was regarded in Western Christianity as a promiscuous woman, claims not found in any of the four canonical gospels. She is a holy patron of Apothecaries; contemplative life; converts; glove makers; hairdressers; penitent sinners; people ridiculed for their piety; perfumeries; pharmacists; sexual temptation; tanners; ​and ​women in general.​

Saint Vincent Ferrer, O.P., (†1419) was a Valencian Dominican friar, who gained acclaim as a missionary and a logician who was canonized by Pope Calixtus III in 1455. His feast day is celebrated on 5 April. He is a holy patron of builders, construction workers, plumbers, fishermen, and orphanages.

Saint Dominic (Spanish: Santo Domingo), also known as Dominic of Osma and Dominic of Caleruega, often called Dominic de Guzmán and Domingo Félix de Guzmán (†1221), was a Castilian priest and founder of the Dominican Order. He is a holy patron of Astronomers; astronomy; Dominican Republic; falsely accused people; Santo Domingo Pueblo, Valletta, Birgu (Malta), and Managua.

Saint Philip Neri, (Italian: Filippo Romolo Neri; † 1595), known as the Apostle of Rome, was an Italian priest noted for founding a society of secular clergy called the Congregation of the Oratory of Filippo Neri. Patron of Rome, Mandaluyong, US Special Forces, Institute of Christ the King Sovereign Priest, laughter, humor, and joy.